| 21) Iso H (2007) | The JACC Study. | 40,964 men, and 55,969 women.
(Japan) | Not defined. | 3,322 men, and
1,950 women. | All cancer mortality | Tukudani (soy sauce-preserved foods) |
| Men: | Women: |
HR = 1.01 (0.91-1.11) for the highest vs lowest tertile of consumption.
Amount specific data:
< 1/w: HR = 1.
1-2/w: HR = 1.01 (0.92-1.10).
≥ 3/w: HR = 1.01 (0.91-1.11).
|
HR = 1.10 (0.98-1.25) for the highest vs lowest tertile of consumption.
Amount specific data:
< 1/w: HR = 1.
1-2/w: HR = 1.03 (0.92-1.16).
≥ 3/w: HR = 1.10 (0.98-1.25).
|
Age and study area. |
| 19) Cutler GJ. (2008) | The Iowa Women's Health Study. | 34,708 postmenopausal women aged 55-69.
(USA) | 1986-2004 | 7,534? | All cancer risk | Soy (not defined) | Stratified by smoking history, intake of soy (≥ 1 vs < 1 time/wk) was not associated with risk of all cancers (No data shown). | Age, energy, education, race, BMI, multivitamin use, activity level, and pack years. |
| 12) Nagata C. (2002) | The Takayama Study. | 13,355 men and 15,724 women aged 35 or older.
(Japan) | 7
(1992-1999) | 400 men, and
253 women | Cancer mortality | Total soy products (tofu, miso, soybeans, natto, soy milk, okara, dried tofu, deep-fried tofu, fried tofu, and fried tofu and minced vegetables/seaweed) |
| Men | Women |
HR = 0.89 (0.64-1.22; P = 0.60) for the highest vs lowest quintile of consumption.
Amount specific data (median intake in g/day):
40.6: HR = 1.
63.9: HR = 0.78 (0.55-1.12).
85.8: HR = 1.10 (0.80-1.52).
114.4: HR = 0.86 (0.62-1.20).
166.4: HR = 0.89 (0.64-1.22). |
HR = 0.79 (0.53-1.18; P = 0.12) for the highest vs lowest quintile of consumption.
Amount specific data (median intake in g/day):
38.5: HR = 1.
60.2: HR = 1.22 (0.83-1.80).
80.0: HR = 0.91 (0.60-1.37).
103.1: HR = 0.98 (0.66-1.46).
148.6: HR = 0.79 (0.53-1.18). |
Age, and total energy.
Additionally for men: marital status, BMI, smoking status, and alcohol intake.
Additionally for women: number of children and history of diabetes mellitus. |
Tofu:
| Auteur | Naam van "cohort" | Onderzoeksgroep | Aantal jaren gevolgd | Aantal personen met kanker | Eind punt | Consumptie van | Relative Risk (RR) | Gecorrigeerd voor |
| 21) Iso H (2007) | The JACC Study. | 44,118 men, and 60,624 women.
(Japan) | Not defined. | 3,683 men, and
2,177 women. | All cancer mortality | Tofu (soybean curd) |
| Men: | Women: |
HR = 0.94 (0.86-1.02) for the highest vs lowest tertile of consumption.
Amount specific data:
< 3/w: HR = 1.
3-4/w: HR = 0.96 (0.88-1.04).
≥ 5/w: HR = 0.94 (0.86-1.02).
|
HR = 0.99 (0.89-1.11) for the highest vs lowest tertile of consumption.
Amount specific data:
< 3/w: HR = 1.
3-4/w: HR = 0.96 (0.89-1.11).
≥ 5/w: HR = 0.99 (0.89-1.11).
|
Age and study area. |
| 16) Khan MM. (2004) | No cohort name. | 1,524 men and 1,634 women aged ≥ 40 living in Hokkaido, Japan. | 1984-2002 | 155 men, 89 women? | Total cancer mortality | Tofu (soybean curd) |
| Men: | Women: |
| RR = 1.2 (0.7-2.1; No P-value). |
RR = 1.4 (0.6-3.4; No P-value). |
RRs are for consumption ≥ several times/wk vs ≤ several times/month.Men: age and smoking. Women: age, health status, health education, health screening + smoking. |
Miso soep (sojaboon pasta):
| Auteur | Naam van "cohort" | Onderzoeksgroep | Aantal jaren gevolgd | Aantal personen met kanker | Eind punt | Consumptie van | Relative Risk (RR) | Gecorrigeerd voor |
| 21) Iso H (2007) | The JACC Study. | 42,696 men, and 58,494 women.
(Japan) | Not defined. | 3,619 men, and
2,156 women. | All cancer mortality | Miso soup |
Men:
| Bowls at present | Bowls at 30 years old |
HR = 0.96 (0.87-1.05) for the highest vs lowest tertile of consumption.
Amount specific data (bowls/day):
< 1: HR = 1.
1: HR = 1.02 (0.92-1.12).
≥ 2: HR = 0.96 (0.87-1.05).
|
HR = 0.99 (0.90-1.08) for the highest vs lowest tertile of consumption.
Amount specific data (bowls/day):
< 1: HR = 1.
1: HR = 0.97 (0.87-1.08).
≥ 2: HR = 0.99 (0.90-1.08).
|
Women:
| Bowls at present | Bowls at 30 years old |
HR = 0.97 (0.87-1.09) for the highest vs lowest tertile of consumption.
Amount specific data (bowls/day):
< 1: HR = 1.
1: HR = 0.92 (0.81-1.04).
≥ 2: HR = 0.97 (0.87-1.09).
|
HR = 0.96 (0.86-1.07) for the highest vs lowest tertile of consumption.
Amount specific data (bowls/day):
< 1: HR = 1.
1: HR = 0.93 (0.81-1.07).
≥ 2: HR = 0.96 (0.86-1.07).
|
Age and study area. |
| 16) Khan MM. (2004) | No cohort name. | 1,524 men and 1,634 women aged ≥ 40 living in Hokkaido, Japan. | 1984-2002 | 155 men, 89 women? | Total cancer mortality | Miso soup |
| Men: | Women: |
| RR = 0.4 (0.1-1.1; No P-value). |
Not estimated due to 0 cases in either of the two groups. |
RRs are for consumption ≥ several times/wk vs ≤ several times/month.Men: age and smoking. Women: age, health status, health education, health screening + smoking. |
| 3) Hirayama T. (1990) | No cohort name. | 265,118 adults (122,261 men, 142,857 women) aged ≥ 40 from 6 prefectures in Japan. | 17
(1966-1982) | 14,740? (8,794 men, 5,946 women) | Cancer at all sites mortality | Soybean paste soup | RR = 0.96 (90% CI = 0.93-0.99; No P-value) for consumption ≥ 4 vs ≤ 3 times/wk. | Age and sex. |
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